Distinct Patterns of Atypical Functional Connectivity in Lower-Functioning Autism
نویسندگان
چکیده
منابع مشابه
Largely typical patterns of resting-state functional connectivity in high-functioning adults with autism.
A leading hypothesis for the neural basis of autism postulates globally abnormal brain connectivity, yet the majority of studies report effects that are either very weak, inconsistent across studies, or explain results incompletely. Here we apply multiple analytical approaches to resting-state BOLD-fMRI data at the whole-brain level. Neurotypical and high-functioning adults with autism displaye...
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OBJECTIVE Connectivity atypicalities in autism spectrum disorders (ASD) have been extensively proposed. The default mode network (DMN) is critical in this study, given the insight it provides for long-distance connectivity, and the importance of regions in this network for introspection and social emotion processing, areas affected in ASD. However, study of this network has largely been limited...
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BACKGROUND Understanding and anticipating others' mental or emotional states relies on the processing of social cues, such as dynamic facial expressions. Individuals with high-functioning autism (HFA) may process these cues differently from individuals with typical development (TD) and purportedly use a 'mechanistic' rather than a 'mentalistic' approach, involving rule- and contingency-based in...
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Background. Unusual gaze behavior in children with autism spectrum disorder (ASD) was reported very early in the literature. Objectives. The current study examined gaze behavior in children with ASD and typically developing (TD) children while performing an active balance task on the Wii balance board. Methods: 8 children (male) diagnosed with high-functioning ASD and 9 TD children (3 female, ...
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Autism spectrum disorder (ASD) is characterized by atypical brain network organization, but findings have been inconsistent. While methodological and maturational factors have been considered, the network specificity of connectivity abnormalities remains incompletely understood. We investigated intrinsic functional connectivity (iFC) for four "core" functional networks-default-mode (DMN), salie...
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ژورنال
عنوان ژورنال: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
سال: 2019
ISSN: 2451-9022
DOI: 10.1016/j.bpsc.2018.08.009